Our journey

Each step on the Adamas journey has been driven by our vision to make everyday life significantly better for people affected by neurological diseases

Al, person with Parkinson’s, talented craftsman


Adamas expands

The FDA approves a second indication for GOCOVRI® (amantadine) extended release capsules as an adjunctive treatment to levodopa/carbidopa for Parkinson’s disease patients experiencing OFF episodes.

We expand our portfolio with the acquisition of a new medicine: OSMOLEX ER® (amantadine) extended release tablets, for the treatment for Parkinson’s disease and drug-induced extrapyramidal reactions in adult patients.



Adamas moving forward

We publish the final results of an open-label study (EASE LID 2) which demonstrate a sustained improvement in levodopa-induced dyskinesia among patients using GOCOVRI.

We are issued a new patent for GOCOVRI that covers a method of reducing ‘OFF’ time and increasing ‘ON’ time without troublesome dyskinesia in people with Parkinson’s disease being treated with levodopa.

The FDA accepts for review our Supplemental New Drug Application (sNDA) for GOCOVRI as a treatment for OFF episodes in Parkinson’s disease patients receiving levodopa-based therapy.



New leadership

Neil McFarlane takes the reins of Adamas as CEO. GOCOVRI sales are $54.6 million for 2019.



GOCOVRI is approved and we launch

GOCOVRI is approved by the FDA in August 2017, our first sale is in November, and we launch commercially in January 2018. We build our national salesforce of neurology specialists.



Namzaric® (memantine HCI and donepezil HCI) launches and Adamas files NDA for GOCOVRI

Namzaric, our partnered drug with Forest Laboratories, a subsidiary of Allergan plc (now part of Abbvie), launches.

We file the NDA for GOCOVRI (ADS-5102).



Phase 3 study in Parkinson’s disease meets primary and secondary endpoints

Our Phase 3 GOCOVRI (ADS-5102) study in Parkinson’s disease meets its primary and key secondary endpoints. Our Phase 2/3 ADS-5102 study is published in Movement Disorders.



A successful IPO

Adamas conducts a successful Initial Public Offering (NASDAQ: ADMS).



Partnership to commercialize Namzaric

Adamas and Forest Laboratories enter into an agreement to commercialize Namzaric, a prescription medicine approved to treat moderate to severe Alzheimer’s disease in patients who are taking donepezil hydrochloride 10 mg, the active ingredient in Aricept®.



Phase 2/3 study focuses on dyskinesia and OFF

Our Phase 2/3 GOCOVRI (ADS-5102) study focuses on dyskinesia and OFF time in patients with Parkinson’s disease, meeting its primary endpoint in 2013.



First Phase 1 clinical studies; we become Adamas

We conduct our initial Phase 1 trials, leading to Namzaric (ADS-8704) and GOCOVRI (ADS-5102).

We become Adamas Pharmaceuticals in July 2007.



Opening in Emeryville

NeuroMolecular moves into offices in Emeryville, CA.



Putting patients first right from the start

Adamas is originally founded as NeuroMolecular, Inc., by Gregory Went, PhD, co-founder of the pioneering genomics firm CuraGen, and several scientific advisors.  He was later joined by key members who helped build the platform and guide the portfolio, including Ivan Lieberburg, MD, PhD, from Athena Neurosciences and Elan, and Efraim Shek, PhD, from Syntex, Cephalon, and Abbott.